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1

Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF

Graeme J Hankey, Manesh R Patel, Susanna R Stevens, Richard C Becker, Günter Breithardt, Antonio Carolei, Hans-Christoph Diener, Geoffrey A Donnan, Jonathan L Halperin, Kenneth W Mahaffey, Jean-Louis

Journal:

The Lancet Neurology

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

2

Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials

Perkovic, Vlado, Zeeuw, Dick de, Mahaffey, Kenneth W, Fulcher, Greg, Erondu, Ngozi, Shaw, Wayne, Barrett, Terrance D, Weidner-Wells, Michele, Deng, Hsiaowei, Matthews, David R, Neal, Bruce

Journal:

The Lancet Diabetes & Endocrinology

Year:

2018

Language:

english

File:

PDF, 498 KB

english, 2018

3

SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis

Neuen, Brendon L, Young, Tamara, Heerspink, Hiddo J L, Neal, Bruce, Perkovic, Vlado, Billot, Laurent, Mahaffey, Kenneth W, Charytan, David M, Wheeler, David C, Arnott, Clare, Bompoint, Severine, Levin

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

4

Risk factors for intracranial hemorrhage and nonhemorrhagic stroke after fibrinolytic therapy (from the GUSTO-i trial)

David E. Kandzari, Christopher B. Granger, Maarten L. Simoons, Harvey D. White, John Simes, Kenneth W. Mahaffey, Joel Gore, W.Douglas Weaver, William T. Longstreth Jr., Amanda Stebbins, Kerry L. Lee,

Journal:

The American Journal of Cardiology

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

5

Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF)

Washam, Jeffrey B, Stevens, Susanna R, Lokhnygina, Yuliya, Halperin, Jonathan L, Breithardt, Günter, Singer, Daniel E, Mahaffey, Kenneth W, Hankey, Graeme J, Berkowitz, Scott D, Nessel, Christopher C,

Journal:

Year:

2015

Language:

english

File:

PDF, 275 KB

english, 2015

6

2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants

Tomaselli, Gordon F., Mahaffey, Kenneth W., Cuker, Adam, Dobesh, Paul P., Doherty, John U., Eikelboom, John W., Florido, Roberta, Hucker, William, Mehran, Roxana, Messé, Steven R., Pollack, Charles V.

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 5.37 MB

english, 2017

7

Sex-Specific Risks of MajorÂ Cardiovascular and LimbÂ EventsÂ inÂ Patients With Symptomatic Peripheral Artery Disease

Haine, Axel, Kavanagh, Sarah, Berger, Jeffrey S., Hess, Connie N., Norgren, Lars, Fowkes, F. Gerry R., Katona, Brian G., Mahaffey, Kenneth W., Blomster, Juuso I., Patel, Manesh R., Jones, W. Schuyler,

Journal:

Journal of the American College of Cardiology

Year:

2020

Language:

english

File:

PDF, 426 KB

english, 2020

8

2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants

Tomaselli, Gordon F., Mahaffey, Kenneth W., Cuker, Adam, Dobesh, Paul P., Doherty, John U., Eikelboom, John W., Florido, Roberta, Gluckman, Ty J., Hucker, William J., Mehran, Roxana, MessÃ©, Steven R.

Journal:

Journal of the American College of Cardiology

Year:

2020

File:

PDF, 958 KB

2020

9

Prevalence, Predictors, and Impact of Conservative Medical Management for Patients With Non–ST-Segment Elevation Acute Coronary Syndromes Who Have Angiographically Documented Significant Coronary Disease

Mark Y. Chan, Kenneth W. Mahaffey, Lena J. Sun, Karen S. Pieper, Harvey D. White, Philip E. Aylward, James J. Ferguson, Robert M. Califf, Matthew T. Roe

Journal:

Journal of the American College of Cardiology: Cardiovascular Interventions

Year:

2008

Language:

english

File:

PDF, 629 KB

english, 2008

10

Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial

Sean van Diepen, Matthew T. Roe, Renato D. Lopes, Amanda Stebbins, Stefan James, L. Kristin Newby, David J. Moliterno, Franz-Josef Neumann, Justin A. Ezekowitz, Kenneth W. Mahaffey, Judith S. Hochman,

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2012

Language:

english

File:

PDF, 235 KB

english, 2012

11

A perspective on trials comparing enoxaparin and unfractionated heparin in the treatment of non–ST-elevation acute coronary syndromes

Robert M. Califf, John L. Petersen, Vic Hasselblad, Kenneth W. Mahaffey, James J. Ferguson

Journal:

American Heart Journal

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005

12

Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non–ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial

Harvey D. White, Neal S. Kleiman, Kenneth W. Mahaffey, Yuliya Lokhnygina, Karen S. Pieper, Karen Chiswell, Marc Cohen, Robert A. Harrington, Derek P. Chew, John L. Petersen, Lisa G. Berdan, Philip E.G

Journal:

American Heart Journal

Year:

2006

Language:

english

File:

PDF, 333 KB

english, 2006

13

Smoking status and antithrombin therapy in patients with non–ST-segment elevation acute coronary syndrome

Steve Leung, Dianne Gallup, Kenneth W. Mahaffey, Marc Cohen, Elliott M. Antman, Shaun G. Goodman, Robert A. Harrington, Anatoly Langer, Philip Aylward, James J. Ferguson, Robert M. Califf

Journal:

American Heart Journal

Year:

2008

Language:

english

File:

PDF, 142 KB

english, 2008

14

Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data

Steg, Philippe Gabriel, Bhatt, Deepak L, Hamm, Christian W, Stone, Gregg W, Gibson, C Michael, Mahaffey, Kenneth W, Leonardi, Sergio, Liu, Tiepu, Skerjanec, Simona, Day, Jonathan R, Iwaoka, Robert S,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.89 MB

english, 2013

15

Efficacy and Bleeding Complications Among Patients Randomized to Enoxaparin or Unfractionated Heparin for Antithrombin Therapy in Non–ST-Segment Elevation Acute Coronary Syndromes

Petersen, John L., Mahaffey, Kenneth W., Hasselblad, Vic, Antman, Elliott M., Cohen, Marc, Goodman, Shaun G., Langer, Anatoly, Blazing, Michael A., Le-Moigne-Amrani, Anne, de Lemos, James A., Nessel,

Journal:

JAMA The Journal of the American Medical Association

Year:

2004

Language:

english

File:

PDF, 120 KB

english, 2004

16

Predictors and Prognostic Implications of Incident Heart Failure in Patients With Prevalent Atrial Fibrillation

Pandey, Ambarish, Kim, Sunghee, Moore, Curtiss, Thomas, Laine, Gersh, Bernard, Allen, Larry A., Kowey, Peter R., Mahaffey, Kenneth W., Hylek, Elaine, Peterson, Eric D., Piccini, Jonathan P., Fonarow,

Journal:

Journal of the American College of Cardiology: Heart Failure

Year:

2017

Language:

english

File:

PDF, 624 KB

english, 2017

17

Ischaemic Events and Stent Thrombosis following Planned Discontinuation of Study Treatment with Ticagrelor or Clopidogrel in the PLATO Study

Storey, Robert, Ardissino, Diego, Vignali, Luigi, Cairns, Richard, Becker, Richard, Cannon, Christopher, Mahaffey, Kenneth, Himmelmann, Anders, Katus, Hugo, James, Stefan, Wallentin, Lars

Journal:

Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 71 KB

english, 2018

18

Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular disease, death and safety outcomes in type 2 diabetes – a systematic review

Rådholm, Karin, HY Wu, Jason, Geot Wong, Muh, Foote, Celine, Fulcher, Gregory, Mahaffey, Kenneth W, Perkovic, Vlado, Neal, Bruce

Journal:

Diabetes Research and Clinical Practice

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

19

Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease – Insights from the STABILITY trial

Held, Claes, White, Harvey D, Stewart, Ralph AH, Davies, Richard, Sampson, Shani, Chiswell, Karen, Silverstein, Adam, Lopes, Renato D., Heldestad, Ulrika, Budaj, Andrzej, Mahaffey, Kenneth W, Wallenti

Journal:

American Heart Journal

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

20

ASSOCIATION BETWEEN GUIDELINE-DIRECTED MEDICAL THERAPIES FOR COMORBID CONDITIONS AND CLINICAL OUTCOMES AMONG INDIVIDUALS WITH ATRIAL FIBRILLATION

Loring, Zak, Shrader, Peter, Allen, Larry, Blanco, Rosalia, Chan, Paul, Ezekowitz, Michael, Fonarow, Gregg, Freeman, James, Gersh, Bernard, Mahaffey, Kenneth, Naccarelli, Gerald, Pieper, Karen, Reiffe

Journal:

Journal of the American College of Cardiology

Year:

2019

Language:

english

File:

PDF, 219 KB

english, 2019

21

Cangrelor in clinical use

Feng, Kent Y, Mahaffey, Kenneth W

Journal:

Future Cardiology

Year:

2020

Language:

english

File:

PDF, 1.35 MB

english, 2020

22

Diabetes and heart failure post-acute myocardial infarction: Important associations and need for evidence-based interventions

Parizo, Justin, Mahaffey, Kenneth W

Journal:

European Journal of Preventive Cardiology

Year:

2020

Language:

english

File:

PDF, 147 KB

english, 2020

23

A Call for a New Paradigm for Diabetes Care in the Era of SodiumâGlucose CotransporterÂ 2 Inhibitors (SGLT2i)

Kim, Sun H., Chang, Tara I., Mahaffey, Kenneth W.

Journal:

Cardiology and Therapy

Year:

2020

File:

PDF, 420 KB

2020

24

Insulin-Like Growth Factor Binding Protein 7 Predicts Renal and Cardiovascular Outcomes in the Canagliflozin Cardiovascular Assessment Study

Januzzi, James L., Butler, Javed, Sattar, Naveed, Xu, Jialin, Shaw, Wayne, Rosenthal, Norman, Pfeifer, Michael, Mahaffey, Kenneth W., Neal, Bruce, Hansen, Michael K.

Journal:

Year:

2020

File:

PDF, 722 KB

2020

25

Utilization of catheterization and revascularization procedures in patients with non-ST segment elevation acute coronary syndrome over the last decade

Glenn N. Levine, A. Michael Lincoff, James J. Ferguson III, Kenneth W. Mahaffey, Shaun G. Goodman, Christopher P. Cannon, Pierre Theroux, Keith A.A. Fox

Journal:

Catheterization and Cardiovascular Interventions

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

26

Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal

Warren J. Cantor, Kenneth W. Mahaffey, Zhen Huang, Pranab Das, Dietrich C. Gulba, Stanislav Glezer, Richard Gallo, John Ducas, Marc Cohen, Elliott M. Antman, Anatoly Langer, Neal S. Kleiman, Harvey D.

Journal:

Catheterization and Cardiovascular Interventions

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

27

Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: A subgroup analysis from the SYNERGY trial

Marc Cohen, Glenn N. Levine, Karen S. Pieper, Lan Lan, Elliott M. Antman, Philip E. Aylward, Harvey D. White, Neal S. Kleiman, Robert M. Califf, Kenneth W. Mahaffey

Journal:

Catheterization and Cardiovascular Interventions

Year:

2010

Language:

english

File:

PDF, 143 KB

english, 2010

28

Enzyme estimates of infarct size correlate with functional and clinical outcomes in the setting of ST-segment elevation myocardial infarction

Aslan T Turer, Kenneth W Mahaffey, Dianne Gallup, W Douglas Weaver, Robert H Christenson, Nathan R Every, E Magnus Ohman

Journal:

Year:

2005

Language:

english

File:

PDF, 457 KB

english, 2005

29

Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study

Kenneth W Mahaffey, Robert A Harrington, Martijn Akkerhuis, Neal S Kleiman, Lisa G Berdan, Brian S Crenshaw, Barbara E Tardiff, Christopher B Granger, Ingrid DeJong, Manju Bhapkar, Petr Widimsky, Ramó

Journal:

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001

30

Systematic adjudication of myocardial infarction end-points in an international clinical trial

Kenneth W Mahaffey, Robert A Harrington, Martijn Akkerhuis, Neal S Kleiman, Lisa G Berdan, Brian S Crenshaw, Barbara E Tardiff, Christopher B Granger, Ingrid DeJong, Manju Bhapkar, Petr Widimsky, Ramó

Journal:

Year:

2001

Language:

english

File:

PDF, 110 KB

english, 2001

31

Low-molecular-weight heparin compared with unfractionated heparin for patients with non–ST-segment elevation acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors: Results from the CRUSADE initiative

Kanwar P. Singh, Matthew T. Roe, Eric D. Peterson, Anita Y. Chen, Kenneth W. Mahaffey, Shaun G. Goodman, Robert A. Harrington, Sidney C. Smith, W. Brian Gibler, E. Magnus Ohman, Charles V. Pollack, fo

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

32

Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome

Richard C. Becker, Kenneth W. Mahaffey, Hongqiu Yang, A. J. Marian, Mark I. Furman, A. Michael Lincoff, Stanley L. Hazen, John L. Petersen, Craig J. Reist, Neal S. Kleiman, SYNERGY Investigators

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2011

Language:

english

File:

PDF, 403 KB

english, 2011

33

Prediction of One-Year Survival in High-Risk Patients with Acute Coronary Syndromes: Results from the SYNERGY Trial

Kenneth W. Mahaffey, Qinghong Yang, Karen S. Pieper, Elliott M. Antman, Harvey D. White, Shaun G. Goodman, Marc Cohen, Neal S. Kleiman, Anatoly Langer, Philip E. Aylward, Jacques J. Col, Craig Reist,

Journal:

Journal of General Internal Medicine

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

34

Anticoagulation for acute coronary syndromes and percutaneous coronary intervention in patients with heparin-induced thrombocytopenia

Kenneth W. Mahaffey

Journal:

Current Cardiology Reports

Year:

2001

Language:

english

File:

PDF, 397 KB

english, 2001

35

The evaluation and management of dyslipidemia and impaired glucose metabolism during acute coronary syndromes

Abhinav Goyal, John L. Petersen, Kenneth W. Mahaffey

Journal:

Current Cardiology Reports

Year:

2004

Language:

english

File:

PDF, 380 KB

english, 2004

36

Promises of PAR-1 Inhibition in Acute Coronary Syndrome

Sergio Leonardi, Pierluigi Tricoci, Kenneth W. Mahaffey

Journal:

Current Cardiology Reports

Year:

2012

Language:

english

File:

PDF, 281 KB

english, 2012

37

Promise of Factor Xa Inhibition in Atrial Fibrillation

Sana M. Al-Khatib, John H. Alexander, Renato D. Lopes, Kenneth W. Mahaffey, Manesh R. Patel, Christopher B. Granger

Journal:

Current Cardiology Reports

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

38

Clopidogrel and PPI Interaction: Clinically Relevant or Not?

Robert W. Harrison, Kenneth W. Mahaffey

Journal:

Current Cardiology Reports

Year:

2012

Language:

english

File:

PDF, 170 KB

english, 2012

39

Determinants of plasma vitamin D levels in patients with acute coronary syndromes

Gabriella Rodriguez, Aijing Z. Starr, Grazyna Z. Czernuszewicz, Amit Manhas, Ahmad Alhariri, James T. Willerson, Craig J. Reist, Karen Pieper, Kenneth W. Mahaffey, Ali J. Marian, Neal S. Kleiman

Journal:

European Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 268 KB

english, 2011

40

Experience with Glycoprotein IIb/IIIa Antagonists in Patients with Acute Coronary Syndromes

DAVID E. KANDZARI, KENNETH W. MAHAFFEY

Journal:

Journal of Interventional Cardiology

Year:

2002

Language:

english

File:

PDF, 1.12 MB

english, 2002

41

Influence of Clinical Trial Participation on Subsequent Antithrombin Use

Bimal R. Shah, Eric D. Peterson, Anita Y. Chen, Kenneth W. Mahaffey, Elizabeth R. DeLong, E. Magnus Ohman, Charles V. Pollack Jr, W. Brian Gibler, Matthew T. Roe

Journal:

Clinical Cardiology

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

42

Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin

Michael P. Thomas, Kenneth W. Mahaffey, Karen Chiswell, Marc Cohen, Michael C. Kontos, Elliott M. Antman, James J. Ferguson, Robert M. Califf, Shaun G. Goodman, Richard C. Becker

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2012

Language:

english

File:

PDF, 268 KB

english, 2012

43

A46 Patient self-addressed postcard follow-up is inadequate: Results from the Duke Clinical Research Institute

Kenneth W. Mahaffey, Barbara E. Tardiff, Christopher B. Granger, Lynn H. Woodlief, Nancy E. Clapp-Channing, Sharon L. Karnash, Bernie McCants, Mary Raney, Kerry L. Lee, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 142 KB

english, 1996

44

A47 Differences in endpoint identification by investigators versus independent review

Barbara E. Tardiff, Kenneth W. Mahaffey, Kristina N. Sigmon, James E. Tcheng, Sharon L. Karnash, Kerry L. Lee, Christopher B. Granger, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 132 KB

english, 1996

45

P29 Prognostic significance of cardiac enzyme elevations detected through systematic screening in clinical trials

Barbara E. Tardiff, Kenneth W. Mahaffey, Kristina N. Sigmon, James E. Tcheng, Sharon L. Karnash, Kerry L. Lee, Christopher B. Granger, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 137 KB

english, 1996

46

P73 Comparison of investigator and central events review of myocardial infarction rates as a means to improve events classification: Results from GUSTO-IIa

Kenneth W. Mahaffey, Barbara E. Tardiff, Christopher B. Granger, Sharon L. Karnash, Lynn H. Woodlief, Kerry L. Lee, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 161 KB

english, 1996

47

P72 An iterative process for defining nonfatal endpoints in the context of clinical trials

Barbara E. Tardiff, Kenneth W. Mahaffey, Sharon I. Karnash, Christopher B. Granger, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 86 KB

english, 1996

48

P31 Reliability of economic and quality of life data for collection of follow-up clinical outcome information

Barbara E. Tardiff, Linda Davidson-Ray, Kenneth W. Mahaffey, Kristina N. Sigmon, Daniel B. Mark, L. Karnash, Christopher B. Granger, Robert M. Califf

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 78 KB

english, 1996

49

P71 Impact of the clinical events committee process on data safety monitoring

Barbara E. Tardiff, Kenneth W. Mahaffey, James E. Tcheng, Christopher B. Granger, Robert M. Califf, Kerry L. Lee

Journal:

Controlled Clinical Trials

Year:

1996

Language:

english

File:

PDF, 86 KB

english, 1996

50

Prognostic usefulness of white blood cell count and temperature in acute myocardial infarction (from the CARDINAL Trial)

Manesh R. Patel, Kenneth W. Mahaffey, Paul W. Armstrong, W. Douglas Weaver, Gudaye Tasissa, Judith S. Hochman, Thomas G. Todaro, Kevin J. Malloy, Scott Rollins, Pierre Theroux, Witold Ruzyllo, Jose C.

Journal:

The American Journal of Cardiology

Year:

2005

Language:

english

File:

PDF, 101 KB

english, 2005